In vivo (normal reproduction) or in vitro fertilization (IVF) of ova (female germ cells) and spermatozoa (male germ cells) forms zygotes which contain the total genetic materials, one half from the male DNA and one half from the female DNA. In favourable condition, the zygote divides and forms the blastomere (8 cells), and then the blastocyst (120-150 cells) around day five. Blastocysts consist of stem cells. At this stage, division of a blastocyst may produce two or more normal human embryos. During the third week of human development, the primitive streak, which is the primitive central nervous system, appears. At this stage, the embryo is a unique entity which is no longer twinnable. Some scientists consider this point as the moment when human life begins as such (Balint, 2001).
Stem cells in blastocysts are capable of differentiating along each of the germ layers of the
ectoderm (skin, nerves, brain), the mesoderm (bone, muscle), and the endoderm (lungs, digestive system) (Hyun, 2008). After this stage of human foetus development, stem cells can be also found in different tissues but their capability is limited. For instance, as Lewis (2009) stated, while mesenchymal stem cells are able to produce bone, cartilage, and muscle, bone marrow stem cells can give rise only to white blood cells. The following part sheds more light on the issue.
Monday, 15 July 2013
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